SR9009 fuala'au 100 papa'a/fagu

Igoa o oloa:SR9009

Avanoa: 10 mg/pill 100 pills/bottle

Tau:$80/fagu

MOQ:1 fagu

Lab:LianFu Bio

Fa'amatalaga o oloa

SR9009, o se REV-ERBagonist, faʻateleina le faʻasalaina o genes faʻatulafonoina e REV-ERBα / ERBβ (IC50: 670/800 nM).E ala i le faʻagaoioia o le REV-ERB, e mafai e le SR9009 ona faʻaitiitia le gaioiga o le locomotor i le taimi o le pogisa ma suia le faʻaaliga mamanu o kenera uati autu i le hypothalami o isumu.O le circadian pattern of expression of a array of metabolic genes in the liver, skeletal muscle, and adipose tissue na suia foi i isumu na faʻaalia i le SR9009, ma mafua ai le faʻateleina o tupe faʻaalu.

SR9009 (100 mg/kg, ip, tauofo, mo le 30 aso) e mafaifa'aitiitia le ga'oma ilogafaʻaleleia le dyslipidemiamahyperglycemia.