Saina Sapalai Sarms Raw Sr9009 Stenabolic API

REV-ERBα ma le REV-ERBβ fa'atosina faaniukilia o transcriptional repressers e faamaopoopo circadian paolo ma metabolic ala i se heme-faalagolago.SR9009 o se REV-ERB agonist lea e faʻapupulaina ai le taofiofia o kenera faʻatonutonu e REV-ERBα ma REV-ERBβ faʻatasi ai ma IC50 tau o 670 ma 800 nM, faasologa.1E ala i le faʻagaoioia o le REV-ERB, SR9009 ua faʻaalia e faʻaitiitia ai le gaioiga o le locomotor i le taimi o le pogisa ma suia le faʻaaliga mamanu o kenera autu o le uati i le hypothalami o isumu.1O le circadian pattern of expression of a array of metabolic genes in the liver, skeletal muscle and adipose tissue na faʻaalia foi le suia i isumu faʻaalia i le SR9009, ma mafua ai le faʻateleina o le faʻaaluina o le malosi. SR9009 (ip faalua i le aso mo le 30 aso) ua lipotia mai e faʻaalia le faʻaitiitia o le gaʻo ma faʻaleleia lelei le dyslipidemia ma le hyperglycemia.1

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